Which type of nutrient can be toxic in excess when stored in the liver?

Fat-soluble vitamins, such as vitamins A, D, E, and K, can accumulate in the liver and other fatty tissues when consumed in excessive amounts. Unlike water-soluble vitamins, which are excreted through urine when taken in excess, fat-soluble vitamins are stored in the body and can lead to toxicity due to their ability to build up over time. For example, excessive intake of vitamin A can cause liver damage and other serious health issues.

In contrast, water-soluble vitamins are typically not stored in large quantities in the body, and any excess is excreted. Dietary fibers do not present toxicity, and while some minerals can be toxic in high amounts, they typically do not have the same storage capability in the liver as fat-soluble vitamins. Hence, fat-soluble vitamins are distinctive in their potential for toxicity when stored in excess.